Search on: CYTOKERATIN 12 
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Descriptor English:   Keratin-12 
Descriptor Spanish:   Queratina-12 
Descriptor Portuguese:   Queratina-12 
Synonyms English:   Cytokeratin-12
Keratin 12
Cytokeratin 12  
Tree Number:   D05.750.078.593.450.300.200
D12.776.220.475.450.300.200
D12.776.860.607.300.200
Definition English:   A type I keratin that is found associated with the KERATIN-3 in the CORNEA and is regarded as a marker for corneal-type epithelial differentiation. Mutations in the gene for keratin-12 have been associated with MEESMANN CORNEAL EPITHELIAL DYSTROPHY. 
Entry Combination - descr/qualif English:   Keratin-12/deficiency use Corneal Dystrophy, Juvenile Epithelial of Meesmann
 
History Note English:   2007(2003) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   52185 
Unique Identifier:   D053551 

Occurrence in VHL:
 

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